Gadolinium Brain Deposition after Macrocyclic Gadolinium Administration: A Pediatric Case-Control Study
نویسندگان
چکیده
منابع مشابه
Macrocyclic Versus Linear Gadolinium Chelates.
T he article “High signal intensity in the dentate nucleus and globus pallidus on unenhanced T1weighted images: evaluation of the macrocyclic gadolinium-based contrast agent gadobutrol” by Radbruch et al provides critical new information regarding gadolinium deposition in the dentate nucleus. The conclusion, from a study of 30 patients, is that no signal intensity increase is seen with gadobutr...
متن کاملHistology and Gadolinium Distribution in the Rodent Brain After the Administration of Cumulative High Doses of Linear and Macrocyclic Gadolinium-Based Contrast Agents
OBJECTIVES Retrospective studies in patients with primary brain tumors or other central nervous system pathologies as well as postmortem studies have suggested that gadolinium (Gd) deposition occurs in the dentate nucleus (DN) and globus pallidus (GP) after multiple administrations of primarily linear Gd-based contrast agents (GBCAs). However, this deposition has not been associated with any ad...
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Nevzat Karabulut Life is continuously confronting us with new issues and sometimes breaking our routine. One case in point is the curious way radiologists’ knowledge about the benefits and risks of gadolinium-based contrast agents (GBCAs) continues to evolve. Significantly improving detection and characterization of lesions in a broad spectrum of diseases, GBCAs have become integral aides to ma...
متن کاملGadolinium encephalopathy after intrathecal gadolinium injection.
BACKGROUND Gadolinium-induced encephalopathy is a well documented complication due to the inadvertent entrance of a high dose of gadolinium into the intrathecal compartment. In lab animals, injecting gadolinium into the intrathecal compartment resulted in neurotoxicity and seizures. It is also well recognized that the presence of autologous blood in the intrathecal compartment can cause a broad...
متن کاملGadolinium deposition in nephrogenic fibrosing dermopathy.
There is growing recognition of the association between the use of gadolinium-containing radiocontrast agents for magnetic resonance imaging and the serious dermal and systemic disease nephrogenic fibrosing dermopathy/nephrogenic systemic fibrosis (NFD/NSF). The pathogenesis of this entity remains unclear; however, our recent observations suggest a likely mechanism for the initial dermal manife...
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ژورنال
عنوان ژورنال: Radiology
سال: 2017
ISSN: 0033-8419,1527-1315
DOI: 10.1148/radiol.2017161151